Human ex vivo data demonstrates the promise of Pathios’ ‘Macrophage Conditioning’ approach in reversing the immunosuppressive polarization of macrophages brought about by an acidic microenvironment.
Data highlights the ability of GPR65 inhibition to bring about a robust Type I/II interferon (IFN) gene signature and reduce tumor burden in a renal cell carcinoma (RCC) PDX model.
Pathios has been awarded £350K (approximately US$475K) in the form a Smart Grant from Innovate UK, the UK Government’s innovation agency, to accelerate their cancer immunotherapy programme targeting the innate...
Pathios has appointed Dr. Tobias Bopp, a leading academic and pioneer in the study of the influence of acidosis on tumour immunology, as the foundational member of its Scientific Advisory...
Pathios has announced a US$8.8M Series A financing round with leading international healthcare investors Canaan and Australia’s Medical Research Commercialisation Fund managed by Brandon Capital (“MRCF”).
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